ASSESSMENT BETWEEN ANTISEPTIC AND NORMAL SALINE FOR NEGATIVE PRESSURE WOUND THERAPY WITH INSTILLATION AND DWELL TIME IN DIABETIC FOOT INFECTIONS

Assessment between antiseptic and normal saline for negative pressure wound therapy with instillation and dwell time in diabetic foot infections

Abstract Negative pressure wound therapy with instillation and dwell time (NPWTi-d) is increasingly used for a diverse range of wounds.Meanwhile, the topical wound irrigation solution consisting of polyhexamethylene biguanide and betaine (PHMB-B) has shown efficacy Girls Easter Dress in managing wound infections.However, the effectiveness of this s

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Renal L-2-hydroxyglutarate dehydrogenase activity promotes hypoxia tolerance and mitochondrial metabolism in Drosophila melanogaster

Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell fate decisions.Loss of L2hgdh activity in humans induces ectopic L-2HG accumulation, resulting in ne

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Complete androgen blockade safely allows for delay of cytotoxic chemotherapy in castration refractory prostate cancer

PURPOSE: Complete androgen blockade (CAB) does not prolong overall survival (OS) in patients with castration refractory prostate cancer (CRPC).Although there is variable clinical benefit with second-line hormone manipulation, we do not know which patients might benefit the most.OBJECTIVES: To identify clinical predictors of benefit Hydrating Gel of

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